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Dr. Ganesh Prabhu

Dr. Ganesh Prabhu completed his Ph.D in 2017 from Shiv Nadar University, Greater Noida, under the able guidance of Prof. N. Sukumar and Dr. Subhabrata Sen where he worked on Diversity-Oriented Synthesis. He published his thesis titled ‘Diversity-Oriented Synthesis of a Molecular Library, Analysis of Molecular Diversity through Network/Graph Measures and Correlation with Biological Activity Profile(s)’.

Dr. Ganesh began his career in 2002 with the New Drug Discovery Department of Orchid Chemical & Pharmaceuticals and later in 2006, he moved to Aurigene Discovery Technologies. He accumulated around 10 years’ experience in Synthesis of New Chemical Entities and Molecular Libraries, Multi-step synthesis, purification, characterization and diversity analysis of synthesized compounds, before joining Shiv Nadar University in 2012 as Ph.D. Scholar and Teaching Assistant. During his professional career spanning 15 years, he has been a part of four patents and six publications while also participating in oral and poster presentations at Scientific Symposiums in India and abroad.

Dr. Ganesh is associated with Sapala Organics since 2018.

Patents

  • WO/2013/088257; Substituted Heterocyclic Compounds As Tropomyosin Receptor Kinase A (Trka) Inhibitors; Dr. Reddy's Laboratories Ltd.; 20-Jun-2013
  • US2009/0239810A1; Novel Piperazine Derivatives as Inhibitors of Stearoyl-CoA Desaturase; Forest Laboratories Holdings Limited; 24-Sep-2009
  • US2009/0239848A1; Novel Piperidine Derivatives as Inhibitors of Stearoyl-CoA Desaturase; Forest Laboratories Holdings Limited; 24-Sep-2009
  • WO2008/010070A2; Novel Oxazolidinone Derivatives; Orchid Research Laboratories; 24-Jan-2008

List of Publications

  • Prabhu, G.; Bhattacharya, S.; Krein, M. P.; Sukumar, N., Investigation of Similarity and Diversity Threshold Networks Generated from Diversity-Oriented and Focused Chemical Libraries. Journal of Mathematical Chemistry 2016, 54 (10), 1916-1941.
  • Prabhu, G.; Agarwal, S.; Sharma, V.; Madurkar, S. M.; Munshi, P.; Singh, S.; Sen, S., A Natural Product Based DOS Library of Hybrid Systems. Eur J Med Chem 2015, 95, 41-8.
  • Sukumar, N.; Krein, M. P.; Prabhu, G.; Bhattacharya, S.; Sen, S.; Network Measures for Chemical Library Design. Drug Dev Res 2014, 75 (6), 402-11.
  • Sen, S.; Prabhu, G.; Bathula, C.; Hati, S.; Diversity-Oriented Asymmetric Synthesis. Synthesis 2014, 46 (16), 2099-2121.
  • Sukumar, N.; Prabhu, G.; Saha P.; Applications of Genetic Algorithms in QSAR/QSPR Modeling. Springer International Publishing, Switzerland, 2014. 315-324.
  • Aaramadaka SK; Guha MK; Prabhu G.; Kini SG; Vijayan M; Synthesis and Evaluation of Urea and Thiourea Derivatives of Oxazolidinones as Antibacterial Agents. Chem Pharm Bull (Tokyo), 2007, 55(2):236-40