1. Sapala has developed multistep synthesis of functionalized cyclopentanoid system (widely used as intermediate in drug synthesis) in kilogram scale using both classical and modern synthetic tools. Ring closing metathesis reaction was performed in multi-gram scale.

2. Sapala has developed a Biotransformation process involving multi-gram scale enzymatic oxidation of amine group of nucleoside to keto group using “ADA” enzyme.

3. Sapala has developed a Biotransformation process involving multi-gram scale regio and stereo specific oxidation of poly-unsaturated fatty acid using “lipoxygenase” have also been performed in multigram scale.

4. Sapala has successfully employed the [2+2] photocycloaddition reaction as a key step to construct bicycle and azabicyclo ring system.

5. Sapala achieved significant break-throughs in Nucleoside chemistry involving the synthesis of a variety of nucleosides using traditional and modern glycosylation techniques.

6. Sapala has a demonstrated track record in carrying out successfully Library Synthesis for Pharmaceutical Companies and Academic Institutions. Sapala is equipped with Parallel Synthesizer which enables efficient synthesis of Library molecules for SAR studies.

7. Sapala has successfully synthesized various novel hetero-aromatic boronates which can be employed for Suzuki Coupling reaction.

8. Sapala has developed novel processes for the synthesis of Polypyridines. A series of Bipyridine and Terpyridine derivatives have been synthesized at Sapala which find applications in Catalysis and Dye Sensitized Solar Cells.

9. Sapala has been successful in the multi-gram scale synthesis of Metal Complexes of bipyridines, terpyridine, porphyrins and phthalocyanines were made in multigram scale.